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1.
Clin Trials ; : 17407745241238444, 2024 Apr 04.
Artículo en Inglés | MEDLINE | ID: mdl-38576071

RESUMEN

BACKGROUND: The Online Resource for Recruitment in Clinical triAls (ORRCA) and the Online Resource for Retention in Clinical triAls (ORRCA2) were established to organise and map the literature addressing participant recruitment and retention within clinical research. The two databases are updated on an ongoing basis using separate but parallel systematic reviews. However, recruitment and retention of research participants is widely acknowledged to be interconnected. While interventions aimed at addressing recruitment challenges can impact retention and vice versa, it is not clear how well they are simultaneously considered within methodological research. This study aims to report the recent update of ORRCA and ORRCA2 with a special emphasis on assessing crossover of the databases and how frequently randomised studies of methodological interventions measure the impact on both recruitment and retention outcomes. METHODS: Two parallel systematic reviews were conducted in line with previously reported methods updating ORRCA (recruitment) and ORRCA2 (retention) with publications from 2018 and 2019. Articles were categorised according to their evidence type (randomised evaluation, non-randomised evaluation, application and observation) and against the recruitment and retention domain frameworks. Articles categorised as randomised evaluations were compared to identify studies appearing in both databases. For randomised studies that were only in one database, domain categories were used to assess whether the methodological intervention was likely to impact on the alternate construct. For example, whether a recruitment intervention might also impact retention. RESULTS: In total, 806 of 17,767 articles screened for the recruitment database and 175 of 18,656 articles screened for the retention database were added as result of the update. Of these, 89 articles were classified as 'randomised evaluation', of which 6 were systematic reviews and 83 were randomised evaluations of methodological interventions. Ten of the randomised studies assessed recruitment and retention and were included in both databases. Of the randomised studies only in the recruitment database, 48/55 (87%) assessed the content or format of participant information which could have an impact on retention. Of the randomised studies only in the retention database, 6/18 (33%) assessed monetary incentives, 4/18 (22%) assessed data collection location and methods and 3/18 (17%) assessed non-monetary incentives, all of which could have an impact on recruitment. CONCLUSION: Only a small proportion of randomised studies of methodological interventions assessed the impact on both recruitment and retention despite having a potential impact on both outcomes. Where possible, an integrated approach analysing both constructs should be the new standard for these types of evaluations to ensure that improvements to recruitment are not at the expense of retention and vice versa.

2.
Water Sci Technol ; 89(6): 1497-1511, 2024 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-38557714

RESUMEN

Identifying vulnerable areas to erosion within the watershed and implementing best management practices (BMPs) are crucial steps in mitigating watershed degradation by minimizing sediment yields. The present study evaluates and identifies the BMPs in the Seybouse basin, northeastern Algeria, using the Soil and Water Assessment Tool (SWAT) model. After successful calibration and validation, the model demonstrated a satisfactory ability to simulate monthly discharge and sediment. Then, the calibrated model was employed to evaluate the efficacy of diverse management practices in sediment control. In the SWAT, three soil and conservation practices, as well as vegetated filter strips (VFSs), grade stabilization structures (GSSs), and terracing were evaluated. The average annual sediment yield in the Seybouse watershed is determined to be 14.43 t/ha year, constituting 71% of the total soil loss. VFS demonstrated a sediment reduction of 37.30%, GSS 20.40%, and terracing 42.30%. Among these strategies, terracing results in the greatest reduction, followed by VFS. The results of this study area can be useful for informed decision-making regarding optimal watershed management strategies.


Asunto(s)
Monitoreo del Ambiente , Sedimentos Geológicos , Sedimentos Geológicos/química , Ríos , Argelia , Modelos Teóricos , Suelo , Agua
3.
Heliyon ; 10(8): e28951, 2024 Apr 30.
Artículo en Inglés | MEDLINE | ID: mdl-38655367

RESUMEN

The hydrological regimes of watersheds might be drastically altered by climate change, a majority of Pakistan's watersheds are experiencing problems with water quality and quantity as a result precipitation changes and temperature, necessitating evaluation and alterations to management strategies. In this study, the regional water security in northern Pakistan is examined about anthropogenic climate change on runoff in the Kunhar River Basin (KRB), a typical river in northern Pakistan using Soil and Water Assessment tool (SWAT) and flow durarion curve (FDC). Nine general circulation models (GCMs) were successfully utilized following bias correction under two latest IPCC shared socioeconomic pathways (SSPs) emission scenarios. Correlation coefficients (R2), Nash-Sutcliffe efficiency coefficients (NSE), and the Percent Bias (PBIAS) are all above 0.75. The conclusions demonstrate that the SWAT model precisely simulates the runoff process in the KRB on monthly and daily timescales. For the two emission scenarios of SSP2-4.5 and SSP5-8.5, the mean annual precipitation is predicted to rise by 3.08 % and 5.86 %, respectively, compared to the 1980-2015 baseline. The forecasted rise in mean daily high temperatures is expected to range from 2.08 °C to 3.07 °C, while the anticipated increase in mean daily low temperatures is projected to fall within the range of 2.09 °C-3.39 °C, spanning the years 2020-2099. Under the two SSPs scenarios, annual runoff is estimated to increase by 5.47 % and 7.60 % due to climate change during the same period. Future socioeconomic growth will be supported by a sufficient water supply made possible by the rise in runoff. However, because of climate change, there is a greater possibility of flooding because of increases in both rainfall and runoff. As a result, flood control and development plans for KRB must consider the climate change's possible effects. There is a chance that the peak flow will move backwards relative to the baseline.

4.
Sci Total Environ ; : 172659, 2024 Apr 22.
Artículo en Inglés | MEDLINE | ID: mdl-38657809

RESUMEN

Identifying which environmental drivers underlie degradation and improvements of ecological communities is a fundamental goal of ecology. Achieving this goal is a challenge due to diverse trends in both environmental conditions and ecological communities across regions, and it is constrained by the lack of long-term parallel monitoring of environmental and community data needed to study causal relationships. Here, we identify key environmental drivers using a high-resolution environmental - ecological dataset, an ensemble of the Soil and Water Assessment Tool (SWAT+) model, and ecological models to investigate effects of climate, land-use, and runoff on the decadal trend (2012-2021) of stream macroinvertebrate communities in a restored urban catchment and an impacted catchment with mixed land uses in Germany. The decadal trends showed decreased precipitation, increased temperature, and reduced anthropogenic land-uses, which led to opposing runoff trends - with decreased runoff in the restored catchment and increased runoff in the impacted catchment. The two catchments also varied in decadal trends of taxonomic and trait composition and metrics. The most significant improvements over time were recorded in communities of the restored catchment sites, which have become wastewater free since 2007 to 2009. Within the restored catchment sites, community metric trends were primarily explained by land-use and evaporation trends, while community composition trends were mostly associated with precipitation and runoff trends. Meanwhile, the communities in the impacted catchment did not undergo significant changes between 2012 and 2021, likely influenced by the effects of prolonged droughts following floods after 2018. The results of our study confirm the significance of restoration and land-use management in fostering long-term improvements in stream communities, while climate change remains a prodigious threat. The coupling of long-term biodiversity monitoring with concurrent sampling of relevant environmental drivers is critical for preventative and restorative management in ecology.

5.
Nicotine Tob Res ; 2024 Mar 21.
Artículo en Inglés | MEDLINE | ID: mdl-38513087

RESUMEN

INTRODUCTION: Poor retention in clinical trials can impact on statistical power, reliability, validity and generalisability of findings and is a particular challenge in smoking cessation studies. In online trials with automated follow up mechanisms, poor response also increases resource-need for manual follow up. This study compared two financial incentives on response rates at 6 months follow up, in an online, automated smoking cessation feasibility trial of a cessation smartphone app (Quit Sense). METHODS: A study within a trial (SWAT), embedded within a host randomised controlled trial. Host trial participants were randomised 1:1 to receive either a £10 or £20 voucher incentive, for completing the 6-month questionnaire. Stratification for randomisation to the SWAT was by minimisation to ensure an even split of host trial arm participants, and by 6-week response rate. Outcome measures were: questionnaire completion rate, time to completion, number of completers requiring manual follow up and completeness of responses. RESULTS: 204 participants were randomised to the SWAT. The £20 and £10 incentives did not differ in completion rate at 6 months (79% versus 74%; p=0.362) but did reduce the proportion of participants requiring manual follow up (46% versus 62%; p=0.018) and the median completion time (7 days versus 15 days; p=0.008). Measure response completeness rates were higher among £20 incentive participants, though differences were small for the host trial's primary smoking outcome. CONCLUSIONS: Benefits to using relatively modest increases in incentive for online smoking cessation trials include more rapid completion of follow up questionnaires and reduced manual follow up. IMPLICATIONS: A modest increase in incentive (from £10 to £20) to promote the completion of follow up questionnaires in online smoking cessation trials may not increase overall response rates but could lead to more rapid data collection, a reduced need for manual follow-up and reduced missing data among those who initiate completing a questionnaire. Such an improvement may help to reduce bias, increase validity and generalisability, and improve statistical power in smoking cessation trials.

6.
J Environ Manage ; 356: 120637, 2024 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-38520859

RESUMEN

Land use/land cover (LULC) change, often a consequence of natural or anthropogenic drivers, plays a decisive role in governing global catchment dynamics, and subsequent impact on regional hydrology. Insight into the complex relationship between the drivers of LULC change and catchment hydrology is of utmost importance to decision makers. Contemplating the dynamic rainfall-runoff response of the Indian catchments, this study proposes an integrated modeling-based approach to identify the drivers and relative contribution to catchment hydrology. The proposed approach was evaluated in the tropical climate Nagavali River Basin (NRB) (9512 km2) of India. The Soil and Water Assessment Tool (SWAT) hydrological model, which uses daily-scale rainfall, temperature, wind speed, relative humidity, solar radiation, and streamflow information was integrated with the Indicators of Hydrologic Alteration (IHA) technique to characterize the plausible changes in the flow regime of the NRB. Subsequently, the Partial Least Squares Regression (PLSR) based modeling analysis was performed to quantify the relative contribution of individual LULC components on the catchment water balance. The outcomes of the study revealed that forest land has been significantly converted to agricultural land (45-59%) across the NRB resulting in mean annual streamflow increase of 3.57 m3/s during the monsoon season. The affinity between land use class and streamflow revealed that barren land (CN = 83-87) exhibits the maximum positive response to streamflow followed by the built-up land (CN = 89-91) and fallow land (CN = 88-93). The period 1985-1995 experienced an increased ET scenario (911-1050 mm), while the recent period (2005-2020) experienced reduced ET scenario owing to conversion of forest to agricultural land. Certainly, the study endorses adopting the developed methodology for understanding the complex land use and catchment-scale hydrologic interactions across global-scales for early watershed management planning.


Asunto(s)
Hidrología , Suelo , Agricultura , Temperatura , Ríos , Agua
7.
Environ Sci Pollut Res Int ; 31(16): 23896-23908, 2024 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-38430443

RESUMEN

Streamflow is a crucial variable for assessing the available water resources for both human and environmental use. Accurate streamflow prediction plays a significant role in water resource management and assessing the impacts of climate change. This study explores the potential of coupling conceptual hydrological models based on physical processes with machine learning algorithms to enhance the performance of streamflow simulations. Four coupled models, namely SWAT-Transformer, SWAT-LSTM, SWAT-GRU, and SWAT-BiLSTM, were constructed in this research. SWAT served as a transfer function to convert four meteorological features, including precipitation, temperature, relative humidity, and wind speed, into six hydrological features: soil water content, lateral flow, percolation, groundwater discharge, surface runoff, and evapotranspiration. Machine learning algorithms were employed to capture the underlying relationships between these ten feature variables and the target variable (streamflow) to predict daily streamflow in the Sandu-River Basin (SRB). Among the four coupled models and the calibrated SWAT model, SWAT-BiLSTM exhibited the best streamflow simulation performance. During the calibration period (training period), it achieved R2 and NSE values of 0.92 and 0.91, respectively, and maintained them at 0.90 during the validation period (testing period). Additionally, the performance of all four coupled models surpassed that of the calibrated SWAT model. Compared to the tendency of the SWAT model to underestimate streamflow, the absolute values of PBIAS for all coupled models are below 10%, which indicates that there is no significant systematic bias evident. SHapley Additive exPlanations (SHAP) were used to analyze the impact of different feature variables on streamflow prediction. The results indicated that precipitation contributed the most to streamflow prediction, with a global importance of 29.7%. Hydrological feature variable output by the SWAT model played a dominant role in the Bi-LSTM's prediction process. Coupling conceptual hydrological models with machine learning algorithms can significantly enhance the predictive performance of streamflow. The application of SHAP improves the interpretability of the coupled models and enhances researchers' confidence in the prediction results.


Asunto(s)
Agua Subterránea , Suelo , Humanos , Abastecimiento de Agua , Recursos Hídricos , Temperatura
8.
Water Res ; 254: 121372, 2024 May 01.
Artículo en Inglés | MEDLINE | ID: mdl-38430761

RESUMEN

Watershed water quality modeling is a valuable tool for managing ammonium (NH4+) pollution. However, simulating NH4+ pollution presents unique challenges due to the inherent instability of NH4+ in natural environment. This study modified the widely-used Soil and Water Assessment Tool (SWAT) model to simulate non-point source (NPS) NH4+ processes, specifically incorporating the simulation of land-to-water NH4+ delivery. The Jiulong River Watershed (JRW) is the study area, a coastal watershed in Southeast China with substantial sewage discharge, livestock farming, and fertilizer application. The results demonstrate that the modified model can effectively simulate the NPS NH4+ processes. It is recommended to use multiple sets of observations to calibrate NH4+ simulation to enhance model reliability. Despite constituting a minor proportion (5.6 %), point source inputs significantly contribute to NH4+ load at watershed outlet (32.4∼51.9 %), while NPS inputs contribute 15.3∼17.3 % of NH4+ loads. NH4+ primarily enters water through surface runoff and lateral flow, with negligible leaching. Average NH4+ land-to-water delivery rate is about 2.35 to 2.90 kg N/ha/a. High delivery rates mainly occur at agricultural areas. Notably, proposed NH4+ mitigation measures, including urban sewage treatment enhancement, livestock manure management improvement, and fertilizer application reduction, demonstrate potential to collectively reduce the NH4+ load at watershed outlet by 1/4 to 1/3 and significantly enhance water quality standard compliance frequency. Insights gained from modeling experience in the JRW offer valuable implications for NH4+ modeling and management in regions with similar climates and significant anthropogenic nitrogen inputs.


Asunto(s)
Compuestos de Amonio , Contaminantes Químicos del Agua , Fertilizantes , Aguas del Alcantarillado , Reproducibilidad de los Resultados , Monitoreo del Ambiente/métodos , Nitrógeno/análisis , Calidad del Agua , China , Ríos , Contaminantes Químicos del Agua/análisis , Fósforo/análisis
9.
Trials ; 25(1): 183, 2024 Mar 12.
Artículo en Inglés | MEDLINE | ID: mdl-38475795

RESUMEN

BACKGROUND: Evidence to support decisions on trial processes is minimal. One way to generate this evidence is to use a Study Within A Trial (SWAT) to test trial processes or explore methodological uncertainties. SWAT evidence relies on replication to ensure sufficient power and broad applicability of findings. Prompt reporting is therefore essential; however, SWAT publications are often the first to be abandoned in the face of other time pressures. Reporting guidance for embedded methodology trials does exist but is not widely used. We sought therefore to build on these guidelines to develop a straightforward, concise reporting standard, which remains adherent to the CONSORT guideline. METHODS: An iterative process was used to develop the guideline. This included initial meetings with key stakeholders, development of an initial guideline, pilot testing of draft guidelines, further iteration and pilot testing, and finalisation of the guideline. RESULTS: We developed a reporting guideline applicable to randomised SWATs, including replications of previous evaluations. The guideline follows the Consolidated Standards for Reporting Trials (CONSORT) statement and provides example text to ensure ease and clarity of reporting across all domains. CONCLUSIONS: The SWAT reporting guideline will aid authors, reviewers, and journal editors to produce and review clear, structured reports of randomised SWATs, whilst also adhering to the CONSORT guideline. TRIAL REGISTRATION: EQUATOR Network - Guidelines Under Development ( https://www.equator-network.org/library/reporting-guidelines-under-development/reporting-guidelines-under-development-for-clinical-trials/#SWAT ). Registered on 25 March 2021.


Asunto(s)
Guías como Asunto , Ensayos Clínicos Controlados Aleatorios como Asunto , Humanos
10.
Ying Yong Sheng Tai Xue Bao ; 35(2): 407-414, 2024 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-38523098

RESUMEN

Assessing the spatiotemporal patterns of watershed water conservation under the influence of the South Asian monsoon climate and its response to precipitation is essential for revealing the evolving patterns of water conservation under different temporal scales. Following the principles of water balance and using the Soil and Water Assessment Tool (SWAT) model, we investigated the spatiotemporal patterns of water conservation and its response to precipitation in the Fangcheng River Basin of Beibu Gulf. The results showed that water conservation in Fangcheng River Basin calculated by SWAT model were 1637.4 mm·a-1, accounting for 50.7% of the mean annual precipitation. The variation of water conservation in different sub-basins was obviously different. Sub-basins with high forest coverage and steep slopes exhibited higher water conservation, while sub-basins with other land use types (such as cropland and grassland), gentle slopes, and intense human activities showed lower water conservation. At the monthly scale, both water conservation and its variation showed similar response characteristics to precipitation in the basin. The response of water conservation variation to sub-precipitation events could be classified into two types. For the short-term rainfall events (duration≤2 days), water conservation variation showed a linear relationship. For the medium to long-term rainfall events (2 days

Asunto(s)
Conservación de los Recursos Hídricos , Ríos , Humanos , Ecosistema , Monitoreo del Ambiente , Suelo , Agua
11.
Environ Sci Pollut Res Int ; 31(15): 23120-23145, 2024 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-38416352

RESUMEN

Prioritization of watersheds is a crucial step in integrated river basin management. It guides resource allocation, planning, decision-making, stakeholder engagement, targeted interventions, and monitoring and evaluation efforts. By identifying and addressing priority watersheds, comprehensive and sustainable management of water resources can be achieved within a river basin. The aim of the current study is to prioritize watersheds using the Soil and Water Assessment Tool (SWAT) and site suitability analysis for the implementation of soil and water conservation structures (SWCS) in the prioritized watersheds by using an analytical hierarchy process (AHP) of the Lower Sutlej Sub-basin, India. The model was calibrated with observed data from 2017 to 2019 with the first 2 years (2015-16) as a warm-up period. Furthermore, validation of the model was done using 2-year data from 2020 to 2021. The model showed successful performance in terms of the R2 range from 0.72 to 0.89, the NSE range from 0.67 to 0.73, the PBIAS range from - 26.70 to 11.30, and the RSR range from 0.51 to 0.57 for stream flow and sediment yield during calibration and validation period. The basin's average annual soil loss ranged from 3.08 to 21.63 t/ha/year, a watershed with the WS2 index seeing the highest rate of soil erosion (21.63 t/ha/year). Hence, WS2 was found to be a top priority. In addition, the site suitability analysis of the prioritized watershed (WS2) reveals that about 1.42% of the area is extremely suitable, 16.14% is highly suitable, and 35.58% is moderately suitable for SWCS. According to the site suitability map validation, both dam locations were found in highly suitable areas, so the developed site suitability map is accurate. This research will help sustainability planners and managers make more informed decisions when building SWCS at suitable sites for better land and water conservation.


Asunto(s)
Suelo , Agua , Suelo/química , Proceso de Jerarquía Analítica , Conservación de los Recursos Naturales , Monitoreo del Ambiente , India
12.
Health Technol Assess ; 28(2): 1-114, 2024 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-38327177

RESUMEN

Background: Randomised controlled trials ('trials') are susceptible to poor participant recruitment and retention. Studies Within A Trial are the strongest methods for testing the effectiveness of strategies to improve recruitment and retention. However, relatively few of these have been conducted. Objectives: PROMoting THE Use of Studies Within A Trial aimed to facilitate at least 25 Studies Within A Trial evaluating recruitment or retention strategies. We share our experience of delivering the PROMoting THE Use of Studies Within A Trial programme, and the lessons learnt for undertaking randomised Studies Within A Trial. Design: A network of 10 Clinical Trials Units and 1 primary care research centre committed to conducting randomised controlled Studies Within A Trial of recruitment and/or retention strategies was established. Promising recruitment and retention strategies were identified from various sources including Cochrane systematic reviews, the Study Within A Trial Repository, and existing prioritisation exercises, which were reviewed by patient and public members to create an initial priority list of seven recruitment and eight retention interventions. Host trial teams could apply for funding and receive support from the PROMoting THE Use of Studies Within A Trial team to undertake Studies Within A Trial. We also tested the feasibility of undertaking co-ordinated Studies Within A Trial, across multiple host trials simultaneously. Setting: Clinical trials unit-based trials recruiting or following up participants in any setting in the United Kingdom were eligible. Participants: Clinical trials unit-based teams undertaking trials in any clinical context in the United Kingdom. Interventions: Funding of up to £5000 and support from the PROMoting THE Use of Studies Within A Trial team to design, implement and report Studies Within A Trial. Main outcome measures: Number of host trials funded. Results: Forty-two Studies Within A Trial were funded (31 host trials), across 12 Clinical Trials Units. The mean cost of a Study Within A Trial was £3535. Twelve Studies Within A Trial tested the same strategy across multiple host trials using a co-ordinated Study Within A Trial design, and four used a factorial design. Two recruitment and five retention strategies were evaluated in more than one host trial. PROMoting THE Use of Studies Within A Trial will add 18% more Studies Within A Trial to the Cochrane systematic review of recruitment strategies, and 79% more Studies Within A Trial to the Cochrane review of retention strategies. For retention, we found that pre-notifying participants by card, letter or e-mail before sending questionnaires was effective, as was the use of pens, and sending personalised text messages to improve questionnaire response. We highlight key lessons learnt to guide others planning Studies Within A Trial, including involving patient and public involvement partners; prioritising and selecting strategies to evaluate and elements to consider when designing a Study Within A Trial; obtaining governance approvals; implementing Studies Within A Trial, including individual and co-ordinated Studies Within A Trials; and reporting Study Within A Trials. Limitations: The COVID-19 pandemic negatively impacted five Studies Within A Trial, being either delayed (n = 2) or prematurely terminated (n = 3). Conclusions: PROMoting THE Use of Studies Within A Trial significantly increased the evidence base for recruitment and retention strategies. When provided with both funding and practical support, host trial teams successfully implemented Studies Within A Trial. Future work: Future research should identify and target gaps in the evidence base, including widening Study Within A Trial uptake, undertaking more complex Studies Within A Trial and translating Study Within A Trial evidence into practice. Study registration: All Studies Within A Trial in the PROMoting THE Use of Studies Within A Trial programme had to be registered with the Northern Ireland Network for Trials Methodology Research Study Within A Trial Repository. Funding: This award was funded by the National Institute for Health and Care Research (NIHR) Health Technology Assessment programme (NIHR award ref: 13/55/80) and is published in full in Health Technology Assessment; Vol. 28, No. 2. See the NIHR Funding and Awards website for further award information.


A Study Within A Trial is a research study nested inside a larger 'host trial', promoting the use of Studies Within A Trial aimed to do Study Within A Trial routine practice in clinical trial units by funding and supporting at least 25 Studies Within A Trial. The best way to test health and social care treatments is to do a randomised controlled trial ('trial'), where some patients get the treatment being tested and some do not. The results of different groups are compared to see if the treatment improves care. Recruiting patients and keeping them involved in trials is often very difficult. Research teams often do not know how best to recruit and keep patients engaged as the methods have not been tested to see if they work. The best way to test these methods is by doing a Study Within A Trial. We test a programme of Studies Within A Trial for recruiting and keeping patients engaged in trials. Trial teams were able to apply for funding of up to £5000 and receive support from Promoting the use of Study Within A Trial team to do Studies Within A Trial. We used our experience of doing Studies Within A Trial to outline lessons learnt for doing Studies Within A Trial. We funded 42 Studies Within A Trial and gave teams necessary advice to do them. We significantly increased the knowledge for both recruitment and retention strategies, and found 'pre-notifying' before sending questionnaires, sending pens and personalised text messages were all effective for increasing responses by participants. We tested Studies Within A Trial across several different trials at the same time to find out more quickly whether their methods worked. We highlight key lessons learnt to guide others doing Studies Within A Trial, including involving patient partners; picking the right strategy to test; getting ethical approvals; how to do and report Studies Within A Trial. Promoting the use of studies within a trial was successful and supported more Studies Within A Trial than planned. We hope our experience will support those doing Studies Within A Trial in the future.


Asunto(s)
Terapia por Ejercicio , Pandemias , Humanos , Análisis Costo-Beneficio , Estudios de Factibilidad , Ensayos Clínicos Controlados Aleatorios como Asunto , Proyectos de Investigación , Encuestas y Cuestionarios , Reino Unido
13.
Contemp Clin Trials Commun ; 38: 101267, 2024 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-38419810

RESUMEN

Background: The use of a second informant (co-respondent) is a common method of identifying potential bias in outcome data (e.g., parent-report child outcomes). There is, however, limited evidence regarding methods of increasing response rates from co-respondents. The use of financial incentives is associated with higher levels of engagement and follow-up data collection in online surveys. This study investigated whether financial incentives paid to index participants in an online trial of a parenting-focused intervention, would lead to higher levels of co-respondent data collection. Methods: A study within a trial (SWAT) using a parallel group RCT design. Participants in the host study (an RCT of an online intervention) were randomised into one of two SWAT arms: received/did not receive a £15 voucher when referred co-respondent completed baseline measures. Primary outcome was completion (No/Yes) of Spence Children's Anxiety Scale (SCAS or SCAS-Pre) at baseline. Additional analysis explored impact of incentives on data quality. Results: Intention to treat analysis of 899 parents (183 co-respondents) in the no-incentive arm, and 911 parents (199 co-respondents) in incentive arm. Nomination of co-respondents was similar between incentive arms. The RR for the incentive arm compared to the no incentive arm was 1.13 (95% CI: 0.91 to 1.41, p = 0.264) indicating that incentives did not impact completion of outcomes by consented co-respondents. There were no indications of different data quality between arms. Discussion: The finding that payment of financial incentives to index participant does not lead to greater levels of co-respondent outcome completion suggests that careful consideration should be made before allocating resources in this way in future trials. Trial registration: The host study was registered at Study Record | ClinicalTrials.gov and the SWAT study was registered in the SWAT Store | The Northern Ireland Network for Trials Methodology Research (qub.ac.uk): SWAT number 143: Filetoupload,1099612,en.pdf (qub.ac.uk).

14.
Environ Monit Assess ; 196(3): 270, 2024 Feb 15.
Artículo en Inglés | MEDLINE | ID: mdl-38358427

RESUMEN

The study investigated the impact of climate and land cover change on water quality. The novel contribution of the study was to investigate the individual and combined impacts of climate and land cover change on water quality with high spatial and temporal resolution in a basin in Turkey. The global circulation model MPI-ESM-MR was dynamically downscaled to 10-km resolution under the RCP8.5 emission scenario. The Soil and Water Assessment Tool (SWAT) was used to model stream flow and nitrate loads. The land cover model outputs that were produced by the Land Change Modeler (LCM) were used for these simulation studies. Results revealed that decreasing precipitation intensity driven by climate change could significantly reduce nitrate transport to surface waters. In the 2075-2100 period, nitrate-nitrogen (NO3-N) loads transported to surface water decreased by more than 75%. Furthermore, the transition predominantly from forestry to pastoral farming systems increased loads by about 6%. The study results indicated that fine-resolution land use and climate data lead to better model performance. Environmental managers can also benefit greatly from the LCM-based forecast of land use changes and the SWAT model's attribution of changes in water quality to land use changes.


Asunto(s)
Cambio Climático , Nitratos , Monitoreo del Ambiente , Transporte Biológico , Agricultura , Suelo
15.
Environ Monit Assess ; 196(3): 294, 2024 Feb 22.
Artículo en Inglés | MEDLINE | ID: mdl-38383760

RESUMEN

The current study investigates the joint impact of projected land use/land cover change (LULCC) and climate change on the discharge of river Puthimari using Soil and Water Assessment Tool (SWAT). Puthimari, flowing through part of Bhutan and the northeastern region of India, earns its significance by contributing a fairly huge amount of discharge to the mainstream Brahmaputra causing frequent floods downstream, specifically in the monsoon season. The analysis was carried out from 2025 to 2099, by dividing this entire period into three sub-periods, 2025‒2049, 2050‒2074, and 2075‒2099, each of 25 years duration. To evaluate the impact of climate change, this study considered future climate data of five different CMIP5 (Coupled Model Intercomparison Project) climate models and their ensemble for RCP4.5 and RCP8.5 (Representative Concentration Pathways). The changes in LULC were incorporated by projecting the future LULC for 2035, 2065, and 2085 for each of the periods using the CA (Cellular Automata)-Markov model. SWAT performed well for both calibration and validation. The respective Nash-Sutcliffe efficiency (NSE) values for calibration and validation were found to be 0.74 and 0.77. Also, 0.75 and 0.79 coefficient of determination (R2) values were obtained for calibration and validation, respectively. The analyses reveal a 19.76% increase in rural settlement, and a 6.30%, 16.45%, and 8.76% decrease in forest, cropland, and waterbodies in the watershed by the end of this century. The average monsoon rainfall would increase by 14.16% and 38.92%, with a corresponding increase in discharge by 34.27% and 64.67%, under RCP 4.5 and RCP 8.5, respectively. This comprehensive study represents a pioneering effort to thoroughly analyze the future hydrological dynamics of the Puthimari River. This research serves as a vital resource for policymakers and government agencies, offering valuable insights to guide both structural and non-structural measures aimed at safeguarding the river from potential flood devastation. Additionally, it provides essential information to support the implementation of effective watershed management practices.


Asunto(s)
Monitoreo del Ambiente , Modelos Teóricos , Inundaciones , Bosques , India , Cambio Climático , Suelo
16.
Environ Monit Assess ; 196(3): 298, 2024 Feb 24.
Artículo en Inglés | MEDLINE | ID: mdl-38396233

RESUMEN

To anticipate disasters (drought, floods, etc.) caused by environmental forcing and reduce their impacts on its fragile economy, sub-Saharan Africa needs a good knowledge of the availability of current water resources and reliable hydroclimatic forecasts. This study has an objective to quantify the availability of water resources in the Nyong basin and predict its future evolution (2024-2050). For this, the SWAT (Soil and Water Assessment Tool) model was used. The performance of this model is satisfactory in calibration (2001-2005) and validation (2006-2010), with R2, NSE, and KGE greater than 0.64. Biases of - 11.8% and - 13.9% in calibration and validation also attest to this good performance. In the investigated basin, infiltration (GW_RCH), evapotranspiration (ETP), surface runoff (SURQ), and water yield (WYLD) are greater in the East, probably due to more abundant rainfall in this part. The flows and sediment load (SED) are greater in the middle zone and in the Southwest of the basin, certainly because of the flat topography of this part, which corresponds to the valley floor. Two climate models (CCCma and REMO) predict a decline in water resources in this basin, and two others (HIRHAM5 and RCA4) are the opposite. However, based on a statistical study carried out over the historical period (2001-2005), the CCCma model seems the most reliable. It forecasts a drop in precipitation and runoff, which do not exceed - 19% and - 18%, respectively, whatever the emission scenario (RCP4.5 or RCP8.5). Climate variability (CV) is the only forcing whose impact is visible in the dynamics of current and future flows, due to the modest current (increase of + 102 km2 in builds and roads) and future (increase of + 114 km2 in builds and roads) changes observed in the evolution of land use and land cover (LULC). The results of this study could contribute to improving water resource management in the basin studied and the region.


Asunto(s)
Monitoreo del Ambiente , Recursos Hídricos , Camerún , Hidrología , Ríos , Bosques , Cambio Climático , Agua
17.
Sci Total Environ ; 915: 170255, 2024 Mar 10.
Artículo en Inglés | MEDLINE | ID: mdl-38246386

RESUMEN

The increase of tree canopy cover due to woody plant encroachment and tree plantations modifies both carbon and water dynamics. The tradeoffs between ecosystem net primary productivity (NPP) and water use with increasing tree cover in different climate conditions, particularly under future climate scenarios, are not well understood. Within the climate transition zone of the southern Great Plains, USA, we used the Soil and Water Assessment Tool+ (SWAT+) to investigate the combined impacts of increasing tree cover and climate change on carbon and water dynamics in three watersheds representing semiarid, subhumid, and humid climates. Model simulations incorporated two land use modifications (Baseline: existing tree cover; Forest +: increasing evergreen tree cover), in conjunction with two climate change projections (the RCP45 and the RCP85), spanning two time periods (historic: 1991-2020; future: 2070-2099). With climate change, the subhumid and humid watersheds exhibited a greater increase in evapotranspiration (ET) and a corresponding reduction in runoff compared to the semi-arid watershed, while the semi-arid and subhumid watersheds encountered pronounced losses in water availability for streams (>200 mm/year) due to increasing tree cover and climate change. With every 1 % increase in tree cover, both NPP and water use efficiency were projected to increase in all three watersheds under both climate change scenarios, with the subhumid watershed demonstrating the largest increases (>0.16 Mg/ha/year and 170 %, respectively). Increasing tree cover within grasslands, either through woody plant expansion or afforestation, boosts ecosystem NPP, particularly in subhumid regions. Nevertheless, this comes with a notable decrease in water resources, a concern made worse by future climate change. While afforestation offers the potential for greater NPP, it also brings heightened water scarcity concerns, highlighting the importance of tailoring carbon sequestration strategies within specific regions to mitigate unintended repercussions on water availability.


Asunto(s)
Cambio Climático , Ecosistema , Agua , Bosques , Árboles , Carbono
18.
J Hazard Mater ; 465: 133461, 2024 Mar 05.
Artículo en Inglés | MEDLINE | ID: mdl-38211526

RESUMEN

This study combined process simulation and actual measurement to construct a multipath diffusion and spatial accumulation model of Cd in a typical lead-zinc mining area through accuracy and root mean square error(RMSE) analysis. The results indicated that (1) the diffusion of Cd was in a quadratic inverse proportional relationship with the distance from the pollution source within watershed. The average annual atmospheric Cd sedimentation in study area was 0.71 * 10-6 g and the contribution of runoff diffusion to Cd exceeded 80%. (2) With the increase in the concentration range of Cd content (k) carried by unit runoff sediment, the model accuracy and RMSE showed decreasing trends. However, when the lower and upper limits of k were 10% and 90%, the model accuracy reached 75%. (3) Two sub-watersheds with same dominant wind direction but different runoff directions were selected to verify the model accuracy, indicating that the model construction method can precisely simulate the spatial accumulation of Cd in similar mining areas. The results provide a scientific basis for the prevention of heavy metal diffusion in lead-zinc mines. Future research should focus on the migration pathways of heavy metals through vertical infiltration caused by rainfall to further optimise the model structure and accuracy.

19.
Environ Monit Assess ; 196(2): 173, 2024 Jan 18.
Artículo en Inglés | MEDLINE | ID: mdl-38236442

RESUMEN

This study establishes a calibrated SWAT (Soil and Water Assessment Tool) model for the Huntai Basin, driven by SSP126, SSP245, SSP585, and multi-model ensemble (MME) models in CMIP6 (Coupled Model Intercomparison Project-6), to investigate the effects of climate change on hydrological processes and pollution load in the Huntai Basin. The results show that the annual mean temperature and the annual precipitation will gradually increase. The nitrogen and phosphorus pollution loads in the basin exhibit a trend of decreasing-increasing-decreasing. The correlation between the nitrogen-phosphorus pollution load and the hydrological process strengthens with increasing radiative forcing. In the four scenarios, CO2 is a primary driving factor that contributes greatly to nitrogen and phosphorus pollution. The main differences are in the total driving factors, and SSP126 and SSP245 are less than those of other models. The total phosphorus and total nitrogen pollution in different climate models were higher than the average level during the benchmark period, except for ammonia nitrogen pollution, which was lower. The nitrogen and phosphorus pollution in SSP126 and SSP245 modes will reach the maximum in 2040s, and the pollution in other periods will be lower than that in SSP585 and MME scenarios. In the long run, the development state between SSP126 and SSP245 may be better appropriate for the Huntai Basin's future sustainable development. This paper analyzes the occurrence and influencing factors of nitrogen and phosphorus pollution under climate change to provide reference to the protection of water environment under changing environments.


Asunto(s)
Cambio Climático , Endrín/análogos & derivados , Monitoreo del Ambiente , Nitrógeno , Fósforo , Agua
20.
Environ Res ; 242: 117810, 2024 Feb 01.
Artículo en Inglés | MEDLINE | ID: mdl-38042516

RESUMEN

Land use/land cover (LULC) is a crucial factor that directly influences the hydrology and water resources of a watershed. In order to assess the impacts of LULC changes on river runoff in the Danjiang River source area, we analyzed the characteristics of LULC data for three time periods (2000, 2010, and 2020). The LULC changes during these periods were quantified, and three Soil and Water Assessment Tool (SWAT) models were established and combined with eight LULC scenarios to quantitatively analyze the effects of LULC changes on river runoff. The results revealed a decrease in the cropland area and an increase in the forest, grassland, and urban land areas from 2000 to 2020. Grassland, forest, and cropland collectively accounted for over 94% of the total area, and conversions among these land types were frequent. The SWAT models constructed based on the LULC data demonstrated good calibration and validation results. Based on the LULC data in three periods, the area of each LULC type changed slightly, so the simulation results were not significantly different. In the subsequent LULC scenarios, we found that the expansion of cropland, grassland, and urban areas was associated with increased river runoff, while an increase in forest area led to a decrease in river runoff. Among the various LULC types, urban land exerted the greatest influence on changes in river runoff. This study establishes three SWAT models and combines multiple LULC scenarios, which is novel and innovative. It can provide scientific basis for the rational allocation of water resources and the optimization of LULC structure in the Danjiang River source area.


Asunto(s)
Suelo , Movimientos del Agua , Ríos , Agua , Hidrología/métodos , China
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